Inside Back Cover: Bioorthogonal Lanthanide Molecular Probes for Near‐Infrared Fluorescence and Mass Spectrometry Imaging (Angew. Chem. Int. Ed. 43/2022)

Spotlights on our sister journals: Angew. Chem. Int. Ed. 15/2018.

MAC it happen : Presented is a study of the synergistic structuredirecting effect of metal–amine complexes (MACs) with different chelating polyamine ligands and imidazolium-based ionic liquid (IL) cations. For the first time, a layered selenidostannate with an asymmetric eight-membered ring, an organic-decorated layered selenidostannate, and a 3D selenidostannate with both the MAC and IL cation...

Molecular probes for fluorescence lifetime imaging.

Visualization of biological processes and pathologic conditions at the cellular and tissue levels largely relies on the use of fluorescence intensity signals from fluorophores or their bioconjugates. To overcome the concentration dependency of intensity measurements, evaluate subtle molecular interactions, and determine biochemical status of intracellular or extracellular microenvironments, flu...

Time-Resolved Fluorescence of Lanthanide Probes and Applications in Biotechnology

Homogenous M13 bacteriophage quantification assay using switchable lanthanide fluorescence probes.

We have developed a rapid and reliable bacteriophage quantification method based on measurement of phage single-stranded DNA (ssDNA) using switchable lanthanide chelate complementation probes. One oligonucleotide probe contains a non-fluorescent lanthanide ion carrier chelate and another probe is labeled with a light absorbing antenna ligand. Hybridization of the non-fluorescent complementation...

Fluorinated Lanthanide (III) Probes for 19F magnetic Resonance Imaging

BACKGROUND New cancer treatments are being developed that exploit the molecular pathology of the disease; however, for the optimal use of these new treatments, functional imaging probes are required to: image the molecular pathology of the cancer noninvasively in order to select the most effective treatment, demonstrate that the drug is reaching the tumour and interacting with its intended targ...